Some think we will gradually understand Everything and others think it is impossible more or less by definition to understand Everything.
In any event, most Everything is still a mystery. There are clues but not much evidence.
Imagination is much faster than Science, so the scientific evidence lag is getting pretty substantial. We aren’t really talking about science any more.
The Big Mystery is what came before the Big Bang.
Millions of humans believe there is a mind at work, and some call that the Mind of God.
Scientists tend to believe as an article of faith that there is no God, it’s all mathematical laws of Nature making everything work like a charm.
But what is Nature?